Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50365936
(CHEMBL1958211)Show SMILES COc1ccc(cc1)C1CC(=NN1c1nc(O)cs1)c1ccc(Br)cc1 |c:11| Show InChI InChI=1S/C19H16BrN3O2S/c1-25-15-8-4-13(5-9-15)17-10-16(12-2-6-14(20)7-3-12)22-23(17)19-21-18(24)11-26-19/h2-9,11,17,24H,10H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of histidine-tagged human recombinant cytoplasmic domain of EGFR expressed in baculovirus infected insect Sf9 cells after 1 hr by DELFIA/t... |
Bioorg Med Chem 20: 2010-8 (2012)
Article DOI: 10.1016/j.bmc.2012.01.051
BindingDB Entry DOI: 10.7270/Q27081WW |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50365936
(CHEMBL1958211)Show SMILES COc1ccc(cc1)C1CC(=NN1c1nc(O)cs1)c1ccc(Br)cc1 |c:11| Show InChI InChI=1S/C19H16BrN3O2S/c1-25-15-8-4-13(5-9-15)17-10-16(12-2-6-14(20)7-3-12)22-23(17)19-21-18(24)11-26-19/h2-9,11,17,24H,10H2,1H3 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University
Curated by ChEMBL
| Assay Description
Inhibition of histidine-tagged human recombinant cytoplasmic domain of HER2 expressed in baculovirus infected insect Sf9 cells after 1 hr by DELFIA/t... |
Bioorg Med Chem 20: 2010-8 (2012)
Article DOI: 10.1016/j.bmc.2012.01.051
BindingDB Entry DOI: 10.7270/Q27081WW |
More data for this
Ligand-Target Pair | |