Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Probable G-protein coupled receptor 142
(Homo sapiens (Human)) | BDBM50390596
(CHEMBL2069576)Show SMILES COc1ccc(cc1NC(=O)[C@H](Cc1ccccc1)NCc1cscn1)-c1ccncc1 |r| Show InChI InChI=1S/C25H24N4O2S/c1-31-24-8-7-20(19-9-11-26-12-10-19)14-22(24)29-25(30)23(13-18-5-3-2-4-6-18)27-15-21-16-32-17-28-21/h2-12,14,16-17,23,27H,13,15H2,1H3,(H,29,30)/t23-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio... |
Bioorg Med Chem Lett 22: 5942-7 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.063
BindingDB Entry DOI: 10.7270/Q2VH5PXT |
More data for this
Ligand-Target Pair | |
Probable G-protein coupled receptor 142
(Homo sapiens (Human)) | BDBM50390596
(CHEMBL2069576)Show SMILES COc1ccc(cc1NC(=O)[C@H](Cc1ccccc1)NCc1cscn1)-c1ccncc1 |r| Show InChI InChI=1S/C25H24N4O2S/c1-31-24-8-7-20(19-9-11-26-12-10-19)14-22(24)29-25(30)23(13-18-5-3-2-4-6-18)27-15-21-16-32-17-28-21/h2-12,14,16-17,23,27H,13,15H2,1H3,(H,29,30)/t23-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 89 | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio... |
Bioorg Med Chem Lett 22: 5942-7 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.063
BindingDB Entry DOI: 10.7270/Q2VH5PXT |
More data for this
Ligand-Target Pair | |