Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50296537
(3,4-dimethoxy-N-(5-(3-(trifluoromethyl)benzyl)thia...)Show SMILES COc1ccc(cc1OC)C(=O)Nc1ncc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C20H17F3N2O3S/c1-27-16-7-6-13(10-17(16)28-2)18(26)25-19-24-11-15(29-19)9-12-4-3-5-14(8-12)20(21,22)23/h3-8,10-11H,9H2,1-2H3,(H,24,25,26) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 mins |
Bioorg Med Chem Lett 19: 4151-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.119
BindingDB Entry DOI: 10.7270/Q21836H1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50296537
(3,4-dimethoxy-N-(5-(3-(trifluoromethyl)benzyl)thia...)Show SMILES COc1ccc(cc1OC)C(=O)Nc1ncc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C20H17F3N2O3S/c1-27-16-7-6-13(10-17(16)28-2)18(26)25-19-24-11-15(29-19)9-12-4-3-5-14(8-12)20(21,22)23/h3-8,10-11H,9H2,1-2H3,(H,24,25,26) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 145 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 mins |
Bioorg Med Chem Lett 19: 4151-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.119
BindingDB Entry DOI: 10.7270/Q21836H1 |
More data for this
Ligand-Target Pair | |