Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Metabotropic glutamate receptor 3
(Homo sapiens (Human)) | BDBM290520
(US10099993, Compound 101)Show SMILES COc1ccc(cc1OCCCCOc1ccc(C(=O)CC(C)(C)C)c(O)c1C)C(=O)N1CCOCC1 Show InChI InChI=1S/C29H39NO7/c1-20-24(11-9-22(27(20)32)23(31)19-29(2,3)4)36-14-6-7-15-37-26-18-21(8-10-25(26)34-5)28(33)30-12-16-35-17-13-30/h8-11,18,32H,6-7,12-17,19H2,1-5H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 741 | n/a | n/a | n/a | n/a |
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
US Patent
| |
US Patent US10099993 (2018)
BindingDB Entry DOI: 10.7270/Q2Z89FFP |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM290520
(US10099993, Compound 101)Show SMILES COc1ccc(cc1OCCCCOc1ccc(C(=O)CC(C)(C)C)c(O)c1C)C(=O)N1CCOCC1 Show InChI InChI=1S/C29H39NO7/c1-20-24(11-9-22(27(20)32)23(31)19-29(2,3)4)36-14-6-7-15-37-26-18-21(8-10-25(26)34-5)28(33)30-12-16-35-17-13-30/h8-11,18,32H,6-7,12-17,19H2,1-5H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 875 | n/a | n/a | 7.3 | 25 |
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
US Patent
| Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (... |
US Patent US10099993 (2018)
BindingDB Entry DOI: 10.7270/Q2Z89FFP |
More data for this
Ligand-Target Pair | |