Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50296296
(CHEMBL563203 | N-(2-(3,5-bis(trifluoromethyl)benzy...)Show SMILES COc1ccc(cc1OCCO)C(=O)Nc1cnc(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)s1 Show InChI InChI=1S/C22H18F6N2O4S/c1-33-16-3-2-13(9-17(16)34-5-4-31)20(32)30-19-11-29-18(35-19)8-12-6-14(21(23,24)25)10-15(7-12)22(26,27)28/h2-3,6-7,9-11,31H,4-5,8H2,1H3,(H,30,32) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of stearoyl-CoA desaturase 1 in human microsome assessed as conversion of [14C]stearate to [14C]oleate |
Bioorg Med Chem Lett 19: 4159-66 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.123
BindingDB Entry DOI: 10.7270/Q2PZ58VW |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50296296
(CHEMBL563203 | N-(2-(3,5-bis(trifluoromethyl)benzy...)Show SMILES COc1ccc(cc1OCCO)C(=O)Nc1cnc(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)s1 Show InChI InChI=1S/C22H18F6N2O4S/c1-33-16-3-2-13(9-17(16)34-5-4-31)20(32)30-19-11-29-18(35-19)8-12-6-14(21(23,24)25)10-15(7-12)22(26,27)28/h2-3,6-7,9-11,31H,4-5,8H2,1H3,(H,30,32) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of stearoyl-CoA desaturase 1 in mouse microsome assessed as conversion of [14C]stearate to [14C]oleate |
Bioorg Med Chem Lett 19: 4159-66 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.123
BindingDB Entry DOI: 10.7270/Q2PZ58VW |
More data for this
Ligand-Target Pair | |