Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50296300
(CHEMBL550785 | N-(5-(hydroxy(3-(trifluoromethyl)ph...)Show SMILES COc1ccc(cc1OCCO)C(=O)Nc1ncc(s1)C(O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H19F3N2O5S/c1-30-15-6-5-13(10-16(15)31-8-7-27)19(29)26-20-25-11-17(32-20)18(28)12-3-2-4-14(9-12)21(22,23)24/h2-6,9-11,18,27-28H,7-8H2,1H3,(H,25,26,29) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 276 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of stearoyl-CoA desaturase 1 in mouse microsome assessed as conversion of [14C]stearate to [14C]oleate |
Bioorg Med Chem Lett 19: 4159-66 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.123
BindingDB Entry DOI: 10.7270/Q2PZ58VW |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50296300
(CHEMBL550785 | N-(5-(hydroxy(3-(trifluoromethyl)ph...)Show SMILES COc1ccc(cc1OCCO)C(=O)Nc1ncc(s1)C(O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H19F3N2O5S/c1-30-15-6-5-13(10-16(15)31-8-7-27)19(29)26-20-25-11-17(32-20)18(28)12-3-2-4-14(9-12)21(22,23)24/h2-6,9-11,18,27-28H,7-8H2,1H3,(H,25,26,29) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 884 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of stearoyl-CoA desaturase 1 in human microsome assessed as conversion of [14C]stearate to [14C]oleate |
Bioorg Med Chem Lett 19: 4159-66 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.123
BindingDB Entry DOI: 10.7270/Q2PZ58VW |
More data for this
Ligand-Target Pair | |