Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM4205
(US8530494, 203)Show SMILES COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35C[C@@H]1COCc1ccc(Cl)cc1)OC |r,TLB:23:22:12.13:19.18| Show InChI InChI=1S/C29H34ClNO4/c1-31-13-12-28-24-19-6-9-22(32-2)25(24)35-26(28)29(33-3)11-10-27(28,23(31)14-19)15-20(29)17-34-16-18-4-7-21(30)8-5-18/h4-9,20,23,26H,10-17H2,1-3H3/t20-,23-,26-,27-,28+,29-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
US Patent
| Assay Description Binding assay of certain compounds of this invention to the opioid receptor was determine using radioligand binding assay (screening and dose-displac... |
US Patent US8530494 (2013)
BindingDB Entry DOI: 10.7270/Q2JS9P3J |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM4205
(US8530494, 203)Show SMILES COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35C[C@@H]1COCc1ccc(Cl)cc1)OC |r,TLB:23:22:12.13:19.18| Show InChI InChI=1S/C29H34ClNO4/c1-31-13-12-28-24-19-6-9-22(32-2)25(24)35-26(28)29(33-3)11-10-27(28,23(31)14-19)15-20(29)17-34-16-18-4-7-21(30)8-5-18/h4-9,20,23,26H,10-17H2,1-3H3/t20-,23-,26-,27-,28+,29-/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 1.47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
US Patent
| Assay Description Binding assay of certain compounds of this invention to the opioid receptor was determine using radioligand binding assay (screening and dose-displac... |
US Patent US8530494 (2013)
BindingDB Entry DOI: 10.7270/Q2JS9P3J |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM4205
(US8530494, 203)Show SMILES COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35C[C@@H]1COCc1ccc(Cl)cc1)OC |r,TLB:23:22:12.13:19.18| Show InChI InChI=1S/C29H34ClNO4/c1-31-13-12-28-24-19-6-9-22(32-2)25(24)35-26(28)29(33-3)11-10-27(28,23(31)14-19)15-20(29)17-34-16-18-4-7-21(30)8-5-18/h4-9,20,23,26H,10-17H2,1-3H3/t20-,23-,26-,27-,28+,29-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 165 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
US Patent
| Assay Description Binding assay of certain compounds of this invention to the opioid receptor was determine using radioligand binding assay (screening and dose-displac... |
US Patent US8530494 (2013)
BindingDB Entry DOI: 10.7270/Q2JS9P3J |
More data for this Ligand-Target Pair | |
Opioid growth factor receptor-like protein 1
(Homo sapiens (Human)) | BDBM4205
(US8530494, 203)Show SMILES COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35C[C@@H]1COCc1ccc(Cl)cc1)OC |r,TLB:23:22:12.13:19.18| Show InChI InChI=1S/C29H34ClNO4/c1-31-13-12-28-24-19-6-9-22(32-2)25(24)35-26(28)29(33-3)11-10-27(28,23(31)14-19)15-20(29)17-34-16-18-4-7-21(30)8-5-18/h4-9,20,23,26H,10-17H2,1-3H3/t20-,23-,26-,27-,28+,29-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 1.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
US Patent
| Assay Description Binding assay of certain compounds of this invention to the opioid receptor was determine using radioligand binding assay (screening and dose-displac... |
US Patent US8530494 (2013)
BindingDB Entry DOI: 10.7270/Q2JS9P3J |
More data for this Ligand-Target Pair | |