Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM4392
(US8530494, 106)Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35C[C@@H]1COCc1ccc(cc1)C(F)(F)F)OC |r,TLB:26:25:15.16:22.21| Show InChI InChI=1S/C33H38F3NO4/c1-38-25-10-7-22-15-26-30-11-12-32(39-2,24(16-30)19-40-18-21-5-8-23(9-6-21)33(34,35)36)29-31(30,27(22)28(25)41-29)13-14-37(26)17-20-3-4-20/h5-10,20,24,26,29H,3-4,11-19H2,1-2H3/t24-,26-,29-,30-,31+,32-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
US Patent
| Assay Description
Binding assay of certain compounds of this invention to the opioid receptor was determine using radioligand binding assay (screening and dose-displac... |
US Patent US8530494 (2013)
BindingDB Entry DOI: 10.7270/Q2JS9P3J |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM4392
(US8530494, 106)Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35C[C@@H]1COCc1ccc(cc1)C(F)(F)F)OC |r,TLB:26:25:15.16:22.21| Show InChI InChI=1S/C33H38F3NO4/c1-38-25-10-7-22-15-26-30-11-12-32(39-2,24(16-30)19-40-18-21-5-8-23(9-6-21)33(34,35)36)29-31(30,27(22)28(25)41-29)13-14-37(26)17-20-3-4-20/h5-10,20,24,26,29H,3-4,11-19H2,1-2H3/t24-,26-,29-,30-,31+,32-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
US Patent
| Assay Description
Binding assay of certain compounds of this invention to the opioid receptor was determine using radioligand binding assay (screening and dose-displac... |
US Patent US8530494 (2013)
BindingDB Entry DOI: 10.7270/Q2JS9P3J |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM4392
(US8530494, 106)Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35C[C@@H]1COCc1ccc(cc1)C(F)(F)F)OC |r,TLB:26:25:15.16:22.21| Show InChI InChI=1S/C33H38F3NO4/c1-38-25-10-7-22-15-26-30-11-12-32(39-2,24(16-30)19-40-18-21-5-8-23(9-6-21)33(34,35)36)29-31(30,27(22)28(25)41-29)13-14-37(26)17-20-3-4-20/h5-10,20,24,26,29H,3-4,11-19H2,1-2H3/t24-,26-,29-,30-,31+,32-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 96.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
US Patent
| Assay Description
Binding assay of certain compounds of this invention to the opioid receptor was determine using radioligand binding assay (screening and dose-displac... |
US Patent US8530494 (2013)
BindingDB Entry DOI: 10.7270/Q2JS9P3J |
More data for this
Ligand-Target Pair | |
Opioid growth factor receptor-like protein 1
(Homo sapiens (Human)) | BDBM4392
(US8530494, 106)Show SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35C[C@@H]1COCc1ccc(cc1)C(F)(F)F)OC |r,TLB:26:25:15.16:22.21| Show InChI InChI=1S/C33H38F3NO4/c1-38-25-10-7-22-15-26-30-11-12-32(39-2,24(16-30)19-40-18-21-5-8-23(9-6-21)33(34,35)36)29-31(30,27(22)28(25)41-29)13-14-37(26)17-20-3-4-20/h5-10,20,24,26,29H,3-4,11-19H2,1-2H3/t24-,26-,29-,30-,31+,32-/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| 3.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
US Patent
| Assay Description
Binding assay of certain compounds of this invention to the opioid receptor was determine using radioligand binding assay (screening and dose-displac... |
US Patent US8530494 (2013)
BindingDB Entry DOI: 10.7270/Q2JS9P3J |
More data for this
Ligand-Target Pair | |