Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM50456465
(CHEMBL4211027)Show SMILES COc1ccc2NC(=O)\C(=N\N(c3ccccc3)c3ccccc3)c2c1 Show InChI InChI=1S/C21H17N3O2/c1-26-17-12-13-19-18(14-17)20(21(25)22-19)23-24(15-8-4-2-5-9-15)16-10-6-3-7-11-16/h2-14H,1H3,(H,22,23,25) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas-CSIC
Curated by ChEMBL
| Assay Description
Inhibition of recombinant catalytic human GST-tagged LLRK2 (970 to 2527 residues) expressed in baculovirus expression system using LRRKtide as substr... |
Eur J Med Chem 138: 328-342 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.060
BindingDB Entry DOI: 10.7270/Q2V40XTP |
More data for this
Ligand-Target Pair | |
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human)) | BDBM50456465
(CHEMBL4211027)Show SMILES COc1ccc2NC(=O)\C(=N\N(c3ccccc3)c3ccccc3)c2c1 Show InChI InChI=1S/C21H17N3O2/c1-26-17-12-13-19-18(14-17)20(21(25)22-19)23-24(15-8-4-2-5-9-15)16-10-6-3-7-11-16/h2-14H,1H3,(H,22,23,25) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaciones Biol�gicas-CSIC
Curated by ChEMBL
| Assay Description
Inhibition of recombinant catalytic human GST-tagged LLRK2 G2019S mutant (970 to 2527 residues) expressed in baculovirus expression system using LRRK... |
Eur J Med Chem 138: 328-342 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.060
BindingDB Entry DOI: 10.7270/Q2V40XTP |
More data for this
Ligand-Target Pair | |