Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50208720
(CHEMBL3884583)Show SMILES COc1ccc2c(c1)[nH]c1c2c(cc2cncc(OC)c12)C(N)=O Show InChI InChI=1S/C18H15N3O3/c1-23-10-3-4-11-13(6-10)21-17-15-9(7-20-8-14(15)24-2)5-12(16(11)17)18(19)22/h3-8,21H,1-2H3,(H2,19,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CDK5/p25 using histone H1 as substrate after 30 mins in presence of [gamma-33 P] ATP by liquid scintillation counting... |
Eur J Med Chem 124: 920-934 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.069
BindingDB Entry DOI: 10.7270/Q24X59S3 |
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50208720
(CHEMBL3884583)Show SMILES COc1ccc2c(c1)[nH]c1c2c(cc2cncc(OC)c12)C(N)=O Show InChI InChI=1S/C18H15N3O3/c1-23-10-3-4-11-13(6-10)21-17-15-9(7-20-8-14(15)24-2)5-12(16(11)17)18(19)22/h3-8,21H,1-2H3,(H2,19,22) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS
Curated by ChEMBL
| Assay Description
Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam... |
Eur J Med Chem 124: 920-934 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.069
BindingDB Entry DOI: 10.7270/Q24X59S3 |
More data for this
Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50208720
(CHEMBL3884583)Show SMILES COc1ccc2c(c1)[nH]c1c2c(cc2cncc(OC)c12)C(N)=O Show InChI InChI=1S/C18H15N3O3/c1-23-10-3-4-11-13(6-10)21-17-15-9(7-20-8-14(15)24-2)5-12(16(11)17)18(19)22/h3-8,21H,1-2H3,(H2,19,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS
Curated by ChEMBL
| Assay Description
Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g... |
Eur J Med Chem 124: 920-934 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.069
BindingDB Entry DOI: 10.7270/Q24X59S3 |
More data for this
Ligand-Target Pair | |