Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50424682
(CHEMBL2313906)Show InChI InChI=1S/C18H15N3OS/c1-11-4-3-5-12(8-11)21-18-17-16(19-10-20-18)14-7-6-13(22-2)9-15(14)23-17/h3-10H,1-2H3,(H,19,20,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50424682
(CHEMBL2313906)Show InChI InChI=1S/C18H15N3OS/c1-11-4-3-5-12(8-11)21-18-17-16(19-10-20-18)14-7-6-13(22-2)9-15(14)23-17/h3-10H,1-2H3,(H,19,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50424682
(CHEMBL2313906)Show InChI InChI=1S/C18H15N3OS/c1-11-4-3-5-12(8-11)21-18-17-16(19-10-20-18)14-7-6-13(22-2)9-15(14)23-17/h3-10H,1-2H3,(H,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rouen
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 59: 283-95 (2013)
Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7 |
More data for this Ligand-Target Pair | |