Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 312.3 BDBM50176522

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50176522 (7-methoxy-3-(3',5'-dimethoxyphenyl)coumarin | CHEM...) Show SMILES COc1ccc2cc(-c3cc(OC)cc(OC)c3)c(=O)oc2c1 Show InChI InChI=1S/C18H16O5/c1-20-13-5-4-11-8-16(18(19)23-17(11)10-13)12-6-14(21-2)9-15(7-12)22-3/h4-10H,1-3H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Noradrenaline induced vasorelaxant activity in intact rat aortic rings				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50176522 (7-methoxy-3-(3',5'-dimethoxyphenyl)coumarin | CHEM...) Show SMILES COc1ccc2cc(-c3cc(OC)cc(OC)c3)c(=O)oc2c1 Show InChI InChI=1S/C18H16O5/c1-20-13-5-4-11-8-16(18(19)23-17(11)10-13)12-6-14(21-2)9-15(7-12)22-3/h4-10H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Inhibition of thrombin-induced platelet aggregation in human				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
					More data for this Ligand-Target Pair