Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 386.4 BDBM50125839

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-serine O-palmitoleoyltransferase porcupine (Homo sapiens (Human))	BDBM50125839 (CHEMBL3623886) Show SMILES COc1ccc2cc(OCC(=O)Nc3ccc(cn3)-c3cnccn3)ccc2c1 Show InChI InChI=1S/C22H18N4O3/c1-28-18-5-2-16-11-19(6-3-15(16)10-18)29-14-22(27)26-21-7-4-17(12-25-21)20-13-23-8-9-24-20/h2-13H,14H2,1H3,(H,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...				Bioorg Med Chem 23: 6855-68 (2015) Article DOI: 10.1016/j.bmc.2015.09.048 BindingDB Entry DOI: 10.7270/Q2J10500
					More data for this Ligand-Target Pair