Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50296534
(6-methoxy-N-(5-(3-(trifluoromethyl)benzyl)thiazol-...)Show SMILES COc1ccc2cc(ccc2c1)C(=O)Nc1ncc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C23H17F3N2O2S/c1-30-19-8-7-15-11-17(6-5-16(15)12-19)21(29)28-22-27-13-20(31-22)10-14-3-2-4-18(9-14)23(24,25)26/h2-9,11-13H,10H2,1H3,(H,27,28,29) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 mins |
Bioorg Med Chem Lett 19: 4151-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.119
BindingDB Entry DOI: 10.7270/Q21836H1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50296534
(6-methoxy-N-(5-(3-(trifluoromethyl)benzyl)thiazol-...)Show SMILES COc1ccc2cc(ccc2c1)C(=O)Nc1ncc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C23H17F3N2O2S/c1-30-19-8-7-15-11-17(6-5-16(15)12-19)21(29)28-22-27-13-20(31-22)10-14-3-2-4-18(9-14)23(24,25)26/h2-9,11-13H,10H2,1H3,(H,27,28,29) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 mins |
Bioorg Med Chem Lett 19: 4151-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.119
BindingDB Entry DOI: 10.7270/Q21836H1 |
More data for this
Ligand-Target Pair | |