Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 311.3 BDBM50239786

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50239786 (CHEMBL4064016) Show SMILES COc1ccc2sc(cc2c1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C18H17NO2S/c1-21-15-7-8-16-14(11-15)12-17(22-16)18(20)19-10-9-13-5-3-2-4-6-13/h2-8,11-12H,9-10H2,1H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged Clk1 expressed in Escherichia coli using RS repeat substrate peptide after 15 mins in presence of [gamma-3...				J Med Chem 60: 5377-5391 (2017) Article DOI: 10.1021/acs.jmedchem.6b01915 BindingDB Entry DOI: 10.7270/Q2862JMM
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