Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysosomal Pro-X carboxypeptidase
(Homo sapiens (Human)) | BDBM193271
(US9193762, RS-33-16)Show SMILES COc1cccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c1 Show InChI InChI=1S/C26H31N3O5/c1-33-21-11-5-10-20(16-21)17-27-24(30)22-12-6-14-28(22)25(31)23-13-7-15-29(23)26(32)34-18-19-8-3-2-4-9-19/h2-5,8-11,16,22-23H,6-7,12-15,17-18H2,1H3,(H,27,30)/t22-,23-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 3.94E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF MISSISSIPPI
US Patent
| Assay Description Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin... |
US Patent US9193762 (2015)
BindingDB Entry DOI: 10.7270/Q2ST7NN2 |
More data for this Ligand-Target Pair | |
Lysosomal Pro-X carboxypeptidase
(Homo sapiens (Human)) | BDBM193271
(US9193762, RS-33-16)Show SMILES COc1cccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c1 Show InChI InChI=1S/C26H31N3O5/c1-33-21-11-5-10-20(16-21)17-27-24(30)22-12-6-14-28(22)25(31)23-13-7-15-29(23)26(32)34-18-19-8-3-2-4-9-19/h2-5,8-11,16,22-23H,6-7,12-15,17-18H2,1H3,(H,27,30)/t22-,23-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| 4.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF MISSISSIPPI
US Patent
| Assay Description Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c... |
US Patent US9193762 (2015)
BindingDB Entry DOI: 10.7270/Q2ST7NN2 |
More data for this Ligand-Target Pair | |