Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 425.4 BDBM50558176

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Mus musculus)	BDBM50558176 (CHEMBL4779679) Show SMILES COc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccnc3ccccc23)c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay				Citation and Details Article DOI: 10.1016/j.bmcl.2016.04.018 BindingDB Entry DOI: 10.7270/Q2HM5D44
					More data for this Ligand-Target Pair
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50558176 (CHEMBL4779679) Show SMILES COc1cccc(NC(=O)N2CCOc3ccc(cc3C2)-c2ccnc3ccccc23)c1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	962	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human GPR142 expressed in CHO cells measured for 3 mins by Fluo-4M dye based FLIPR assay				Citation and Details Article DOI: 10.1016/j.bmcl.2016.04.018 BindingDB Entry DOI: 10.7270/Q2HM5D44
					More data for this Ligand-Target Pair