Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 464.4 BDBM360584

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360584 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-2...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)C(C)c2ccc(cc2)C(F)(F)F)c2cnccc12 Show InChI InChI=1S/C27H23F3N2O2/c1-17(18-6-9-21(10-7-18)27(28,29)30)26(33)32-15-20-8-11-23(24-12-13-31-16-25(20)24)19-4-3-5-22(14-19)34-2/h3-14,16-17H,15H2,1-2H3,(H,32,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	566	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair