Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 451.5 BDBM360527

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360527 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-4...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)c2ccc(cc2)N2CCCCC2)c2cnccc12 Show InChI InChI=1S/C29H29N3O2/c1-34-25-7-5-6-22(18-25)26-13-10-23(28-20-30-15-14-27(26)28)19-31-29(33)21-8-11-24(12-9-21)32-16-3-2-4-17-32/h5-15,18,20H,2-4,16-17,19H2,1H3,(H,31,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	988	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair