Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
17-beta-hydroxysteroid dehydrogenase type 3
(Homo sapiens (Human)) | BDBM50179937
(1-[2-chloro-8-(3-methoxy-phenyl)-11,12-dihydro-6H-...)Show SMILES COc1cccc(c1)-c1ccc2CCc3cc(Cl)ccc3N(Cc2c1)C(C)=O Show InChI InChI=1S/C24H22ClNO2/c1-16(27)26-15-21-12-19(18-4-3-5-23(14-18)28-2)8-6-17(21)7-9-20-13-22(25)10-11-24(20)26/h3-6,8,10-14H,7,9,15H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of 17beta-HSD3 |
Bioorg Med Chem Lett 16: 1532-6 (2006)
Article DOI: 10.1016/j.bmcl.2005.12.039 BindingDB Entry DOI: 10.7270/Q2CV4HBV |
More data for this Ligand-Target Pair | |
17-beta-hydroxysteroid dehydrogenase type 3
(Homo sapiens (Human)) | BDBM50179937
(1-[2-chloro-8-(3-methoxy-phenyl)-11,12-dihydro-6H-...)Show SMILES COc1cccc(c1)-c1ccc2CCc3cc(Cl)ccc3N(Cc2c1)C(C)=O Show InChI InChI=1S/C24H22ClNO2/c1-16(27)26-15-21-12-19(18-4-3-5-23(14-18)28-2)8-6-17(21)7-9-20-13-22(25)10-11-24(20)26/h3-6,8,10-14H,7,9,15H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of 17beta-HSD3 by SEAP assay |
Bioorg Med Chem Lett 16: 1532-6 (2006)
Article DOI: 10.1016/j.bmcl.2005.12.039 BindingDB Entry DOI: 10.7270/Q2CV4HBV |
More data for this Ligand-Target Pair | |