Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitogen-activated protein kinase kinase kinase kinase 4
(Homo sapiens (Human)) | BDBM299619
(6-(3-methoxy- phenyl) pyrido[3,2-d] pyrimidin- 4-a...)Show InChI InChI=1S/C14H12N4O/c1-19-10-4-2-3-9(7-10)11-5-6-12-13(18-11)14(15)17-8-16-12/h2-8H,1H3,(H2,15,16,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 99.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
| Assay Description The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ... |
J Med Chem 46: 3709-27 (2003)
BindingDB Entry DOI: 10.7270/Q2VH5R4B |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 4
(Homo sapiens (Human)) | BDBM299619
(6-(3-methoxy- phenyl) pyrido[3,2-d] pyrimidin- 4-a...)Show InChI InChI=1S/C14H12N4O/c1-19-10-4-2-3-9(7-10)11-5-6-12-13(18-11)14(15)17-8-16-12/h2-8H,1H3,(H2,15,16,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 99.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech, Inc.
US Patent
| Assay Description The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ... |
US Patent US9592235 (2017)
BindingDB Entry DOI: 10.7270/Q2VX0JKX |
More data for this Ligand-Target Pair | |