Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 478.5 BDBM486402

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM486402 (N-(1,1-dioxidotetrahydrothiophen- 3-yl)-1-(4-fluor...) Show SMILES COc1cccc(c1)-c1cn(-c2ccc(F)cc2)c2cc(ccc12)C(=O)NC1CCS(=O)(=O)C1 Show InChI InChI=1S/C26H23FN2O4S/c1-33-22-4-2-3-17(13-22)24-15-29(21-8-6-19(27)7-9-21)25-14-18(5-10-23(24)25)26(30)28-20-11-12-34(31,32)16-20/h2-10,13-15,20H,11-12,16H2,1H3,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US10947222 (2021) BindingDB Entry DOI: 10.7270/Q20P134X
					More data for this Ligand-Target Pair