Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM440709
(US10639284, Compound 2.060 | US11426364, Compound ...)Show SMILES COc1cccc(c1F)-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CCC[C@H](O)C2)cc1Cl |r| Show InChI InChI=1S/C35H33ClFN3O4/c1-42-32-9-3-8-29(35(32)37)26-6-2-7-28-27(26)10-11-31(28)44-34-15-33(43-21-23-13-22(16-38)17-39-18-23)24(14-30(34)36)19-40-12-4-5-25(41)20-40/h2-3,6-9,13-15,17-18,25,31,41H,4-5,10-12,19-21H2,1H3/t25-,31-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2K93BSK |
More data for this
Ligand-Target Pair | |
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM440709
(US10639284, Compound 2.060 | US11426364, Compound ...)Show SMILES COc1cccc(c1F)-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CCC[C@H](O)C2)cc1Cl |r| Show InChI InChI=1S/C35H33ClFN3O4/c1-42-32-9-3-8-29(35(32)37)26-6-2-7-28-27(26)10-11-31(28)44-34-15-33(43-21-23-13-22(16-38)17-39-18-23)24(14-30(34)36)19-40-12-4-5-25(41)20-40/h2-3,6-9,13-15,17-18,25,31,41H,4-5,10-12,19-21H2,1H3/t25-,31-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc.
US Patent
| Assay Description
Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% BSA... |
US Patent US10639284 (2020)
BindingDB Entry DOI: 10.7270/Q25Q5043 |
More data for this
Ligand-Target Pair | |