Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 188.1 BDBM50569358

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50569358 (CHEMBL1989223) Show SMILES COc1cccc2C(=O)C=CC(=O)c12 |c:9| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DNA topoisomerase 1 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.127976 BindingDB Entry DOI: 10.7270/Q2S75M49
					More data for this Ligand-Target Pair