Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acetyl-CoA carboxylase 1
(Homo sapiens (Human)) | BDBM496969
(US10995099, Example 59)Show SMILES COc1ccccc1[C@H](Cn1c2sc(Br)c(C)c2c(=O)n(c1=O)C1(CC(O)=O)CC1)OC1CCOCC1 |r| Show InChI InChI=1S/C26H29BrN2O7S/c1-15-21-23(32)29(26(9-10-26)13-20(30)31)25(33)28(24(21)37-22(15)27)14-19(36-16-7-11-35-12-8-16)17-5-3-4-6-18(17)34-2/h3-6,16,19H,7-14H2,1-2H3,(H,30,31)/t19-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Ruijie Pharmatech Co., Ltd.
US Patent
| Assay Description
An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa... |
US Patent US10995099 (2021)
BindingDB Entry DOI: 10.7270/Q2028VPN |
More data for this
Ligand-Target Pair | |
Acetyl-CoA carboxylase 2
(Homo sapiens (Human)) | BDBM496969
(US10995099, Example 59)Show SMILES COc1ccccc1[C@H](Cn1c2sc(Br)c(C)c2c(=O)n(c1=O)C1(CC(O)=O)CC1)OC1CCOCC1 |r| Show InChI InChI=1S/C26H29BrN2O7S/c1-15-21-23(32)29(26(9-10-26)13-20(30)31)25(33)28(24(21)37-22(15)27)14-19(36-16-7-11-35-12-8-16)17-5-3-4-6-18(17)34-2/h3-6,16,19H,7-14H2,1-2H3,(H,30,31)/t19-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Ruijie Pharmatech Co., Ltd.
US Patent
| Assay Description
An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa... |
US Patent US10995099 (2021)
BindingDB Entry DOI: 10.7270/Q2028VPN |
More data for this
Ligand-Target Pair | |