Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 261.2 BDBM50509160

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein (Hepatitis C virus)	BDBM50509160 (CHEMBL4570983) Show SMILES COc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO5/c1-19-10-5-3-2-4-7(10)8-6-9(15)12(16)11(14-8)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509160 (CHEMBL4570983) Show SMILES COc1ccccc1-c1cc(=O)c(O)c([nH]1)C(O)=O Show InChI InChI=1S/C13H11NO5/c1-19-10-5-3-2-4-7(10)8-6-9(15)12(16)11(14-8)13(17)18/h2-6,16H,1H3,(H,14,15)(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair