Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 322.4 BDBM50585883

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ceramide glucosyltransferase (Homo sapiens (Human))	BDBM50585883 (CHEMBL5085627) Show SMILES COc1ccccc1-c1nccc2C(=O)N(Cc12)C1CCCCC1 Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hr by RapidFire mass spectrometry				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02078 BindingDB Entry DOI: 10.7270/Q2KW5KZB
					More data for this Ligand-Target Pair