Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Acetyl-CoA carboxylase 1
(Homo sapiens (Human)) | BDBM496912
(US10995099, Example 46)Show SMILES COc1ccccc1C(Cn1c2sc(c(C)c2c(=O)n(c1=O)C1(CC1)C(N)=O)-c1ncco1)OC1CCOCC1 Show InChI InChI=1S/C28H30N4O7S/c1-16-21-24(33)32(28(9-10-28)26(29)34)27(35)31(25(21)40-22(16)23-30-11-14-38-23)15-20(39-17-7-12-37-13-8-17)18-5-3-4-6-19(18)36-2/h3-6,11,14,17,20H,7-10,12-13,15H2,1-2H3,(H2,29,34) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Ruijie Pharmatech Co., Ltd.
US Patent
| Assay Description An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa... |
US Patent US10995099 (2021)
BindingDB Entry DOI: 10.7270/Q2028VPN |
More data for this Ligand-Target Pair | |
Acetyl-CoA carboxylase 2
(Homo sapiens (Human)) | BDBM496912
(US10995099, Example 46)Show SMILES COc1ccccc1C(Cn1c2sc(c(C)c2c(=O)n(c1=O)C1(CC1)C(N)=O)-c1ncco1)OC1CCOCC1 Show InChI InChI=1S/C28H30N4O7S/c1-16-21-24(33)32(28(9-10-28)26(29)34)27(35)31(25(21)40-22(16)23-30-11-14-38-23)15-20(39-17-7-12-37-13-8-17)18-5-3-4-6-19(18)36-2/h3-6,11,14,17,20H,7-10,12-13,15H2,1-2H3,(H2,29,34) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Ruijie Pharmatech Co., Ltd.
US Patent
| Assay Description An exemplary procedure for the in vitro ACC inhibition assay, which can be used to determine the inhibitory action of compounds of the invention towa... |
US Patent US10995099 (2021)
BindingDB Entry DOI: 10.7270/Q2028VPN |
More data for this Ligand-Target Pair | |