Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Solute carrier family 2, facilitated glucose transporter member 1
(Homo sapiens (Human)) | BDBM50155754
(CHEMBL3780729)Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)C(C)c1ccccc1 Show InChI InChI=1S/C24H26N6O/c1-18(19-8-4-3-5-9-19)30-24-20(16-27-30)23(25-17-26-24)29-14-12-28(13-15-29)21-10-6-7-11-22(21)31-2/h3-11,16-18H,12-15H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma AG
Curated by ChEMBL
| Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr... |
Bioorg Med Chem Lett 26: 1732-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3 |
More data for this Ligand-Target Pair | |
Solute carrier family 2, facilitated glucose transporter member 3
(Homo sapiens (Human)) | BDBM50155754
(CHEMBL3780729)Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)C(C)c1ccccc1 Show InChI InChI=1S/C24H26N6O/c1-18(19-8-4-3-5-9-19)30-24-20(16-27-30)23(25-17-26-24)29-14-12-28(13-15-29)21-10-6-7-11-22(21)31-2/h3-11,16-18H,12-15H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma AG
Curated by ChEMBL
| Assay Description Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter... |
Bioorg Med Chem Lett 26: 1732-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3 |
More data for this Ligand-Target Pair | |
Solute carrier family 2, facilitated glucose transporter member 2
(Homo sapiens (Human)) | BDBM50155754
(CHEMBL3780729)Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)C(C)c1ccccc1 Show InChI InChI=1S/C24H26N6O/c1-18(19-8-4-3-5-9-19)30-24-20(16-27-30)23(25-17-26-24)29-14-12-28(13-15-29)21-10-6-7-11-22(21)31-2/h3-11,16-18H,12-15H2,1-2H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma AG
Curated by ChEMBL
| Assay Description Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre... |
Bioorg Med Chem Lett 26: 1732-7 (2016)
Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3 |
More data for this Ligand-Target Pair | |