Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM50099459
(CHEMBL3342869)Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(OC(F)(F)F)cc3)O2)CC1 Show InChI InChI=1S/C18H14N4O6/c23-12(24)6-3-7-28-21-14-10-5-2-1-4-9(10)13-15(14)22-8-11(18(26)27)19-16(22)17(25)20-13/h1-2,4-5,8H,3,6-7H2,(H,20,25)(H,23,24)(H,26,27)/b21-14+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Modena e Reggio Emilia
Curated by ChEMBL
| Assay Description
Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Eur J Med Chem 87: 248-66 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4 |
More data for this
Ligand-Target Pair | |
Alpha-1D adrenergic receptor
(Homo sapiens (Human)) | BDBM50099459
(CHEMBL3342869)Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(OC(F)(F)F)cc3)O2)CC1 Show InChI InChI=1S/C18H14N4O6/c23-12(24)6-3-7-28-21-14-10-5-2-1-4-9(10)13-15(14)22-8-11(18(26)27)19-16(22)17(25)20-13/h1-2,4-5,8H,3,6-7H2,(H,20,25)(H,23,24)(H,26,27)/b21-14+ | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Modena e Reggio Emilia
Curated by ChEMBL
| Assay Description
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Eur J Med Chem 87: 248-66 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50099459
(CHEMBL3342869)Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(OC(F)(F)F)cc3)O2)CC1 Show InChI InChI=1S/C18H14N4O6/c23-12(24)6-3-7-28-21-14-10-5-2-1-4-9(10)13-15(14)22-8-11(18(26)27)19-16(22)17(25)20-13/h1-2,4-5,8H,3,6-7H2,(H,20,25)(H,23,24)(H,26,27)/b21-14+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Modena e Reggio Emilia
Curated by ChEMBL
| Assay Description
Displacement of [3H]8-OH-DPAT from human recombinant 5-HT1A receptor expressed in HeLa cells after 30 mins by liquid scintillation counting |
Eur J Med Chem 87: 248-66 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4 |
More data for this
Ligand-Target Pair | |
Alpha-1B adrenergic receptor
(Homo sapiens (Human)) | BDBM50099459
(CHEMBL3342869)Show SMILES COc1ccccc1N1CCN(CC2COC3(CCN(CC3)S(=O)(=O)c3ccc(OC(F)(F)F)cc3)O2)CC1 Show InChI InChI=1S/C18H14N4O6/c23-12(24)6-3-7-28-21-14-10-5-2-1-4-9(10)13-15(14)22-8-11(18(26)27)19-16(22)17(25)20-13/h1-2,4-5,8H,3,6-7H2,(H,20,25)(H,23,24)(H,26,27)/b21-14+ | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 148 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Modena e Reggio Emilia
Curated by ChEMBL
| Assay Description
Displacement of [3H]prazosin from human recombinant alpha1B adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation counting |
Eur J Med Chem 87: 248-66 (2014)
Article DOI: 10.1016/j.ejmech.2014.09.070
BindingDB Entry DOI: 10.7270/Q20G3MX4 |
More data for this
Ligand-Target Pair | |