Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 427.9 BDBM50073926

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50073926 (CHEMBL3409468) Show SMILES COc1ccccc1Nc1ccc(cc1Cl)C(=O)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C24H30ClN3O2/c1-30-23-8-4-3-7-22(23)26-21-10-9-18(17-20(21)25)24(29)28-15-11-19(12-16-28)27-13-5-2-6-14-27/h3-4,7-10,17,19,26H,2,5-6,11-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Inhibition of LRRK2 G2019S mutant (1326 to 252 aa) (unknown origin) stably expressed in HEK293 cell lysate using [gamma-32P] after 15 mins by Cerenko...				Eur J Med Chem 95: 29-34 (2015) Article DOI: 10.1016/j.ejmech.2015.03.003 BindingDB Entry DOI: 10.7270/Q2TH8PDX
					More data for this Ligand-Target Pair