Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 473.5 BDBM251720

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysophosphatidic acid receptor 5 (Homo sapiens (Human))	BDBM251720 (US9464060, 56) Show SMILES COc1ccccc1O[C@H]1CC[C@@H](CC1)C(=O)N(Cc1ccccc1)Cc1ccc(cc1)C(O)=O |r,wU:12.16,wD:9.9,(-8.67,-4.23,;-7.34,-3.46,;-7.34,-1.93,;-8.67,-1.16,;-8.67,.38,;-7.34,1.15,;-6,.38,;-6,-1.16,;-4.67,-1.93,;-3.33,-1.16,;-2,-1.93,;-.67,-1.16,;-.67,.38,;-2,1.15,;-3.33,.38,;.67,1.15,;.67,2.69,;2,.38,;3.33,1.15,;3.33,2.69,;4.67,3.46,;4.67,5,;3.33,5.77,;2,5,;2,3.46,;2,-1.16,;3.33,-1.93,;3.33,-3.47,;4.67,-4.24,;6,-3.47,;6,-1.93,;4.67,-1.16,;7.34,-4.24,;7.34,-5.77,;8.67,-3.47,)| Show InChI InChI=1S/C29H31NO5/c1-34-26-9-5-6-10-27(26)35-25-17-15-23(16-18-25)28(31)30(19-21-7-3-2-4-8-21)20-22-11-13-24(14-12-22)29(32)33/h2-14,23,25H,15-20H2,1H3,(H,32,33)/t23-,25-	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	37
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA5 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...				US Patent US9464060 (2016) BindingDB Entry DOI: 10.7270/Q23R0RT0
					More data for this Ligand-Target Pair