Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 498.5 BDBM389801

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM389801 (2-Imidazo[4,5-b]pyridin-3-yl-1-{(R)-4-[2-(6-methox...) Show SMILES COc1cncc(n1)N1CCc2cccc(N3CCN([C@H](C)C3)C(=O)Cn3cnc4cccnc34)c2C1 Show InChI InChI=1S/C27H30N8O2/c1-19-15-32(11-12-35(19)26(36)17-34-18-30-22-6-4-9-29-27(22)34)23-7-3-5-20-8-10-33(16-21(20)23)24-13-28-14-25(31-24)37-2/h3-7,9,13-14,18-19H,8,10-12,15-17H2,1-2H3/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.03	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				Bioorg Med Chem Lett 17: 3473-9 (2007) BindingDB Entry DOI: 10.7270/Q20R9RRK
					More data for this Ligand-Target Pair