Found 6 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human)) | BDBM286370
(US11220518, Ex. No. K26 | US11780853, Example K26 ...)Show SMILES COc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C21H31FN8O3/c1-12-9-28(4)13(6-7-31)10-29(12)20(32)30-11-14-16(21(30,2)3)26-27-17(14)24-18-15(22)8-23-19(25-18)33-5/h8,12-13,31H,6-7,9-11H2,1-5H3,(H2,23,24,25,26,27)/t12-,13?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| 36.5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
PFIZER INC.
US Patent
| Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe... |
US Patent US9518060 (2016)
BindingDB Entry DOI: 10.7270/Q2ZK5JPN |
More data for this
Ligand-Target Pair | |
Protein kinase C beta type
(Homo sapiens (Human)) | BDBM286370
(US11220518, Ex. No. K26 | US11780853, Example K26 ...)Show SMILES COc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C21H31FN8O3/c1-12-9-28(4)13(6-7-31)10-29(12)20(32)30-11-14-16(21(30,2)3)26-27-17(14)24-18-15(22)8-23-19(25-18)33-5/h8,12-13,31H,6-7,9-11H2,1-5H3,(H2,23,24,25,26,27)/t12-,13?/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 36.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q28S4T3T |
More data for this
Ligand-Target Pair | |
Protein kinase C beta type Isoform 2
(Homo sapiens (Human)) | BDBM286370
(US11220518, Ex. No. K26 | US11780853, Example K26 ...)Show SMILES COc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C21H31FN8O3/c1-12-9-28(4)13(6-7-31)10-29(12)20(32)30-11-14-16(21(30,2)3)26-27-17(14)24-18-15(22)8-23-19(25-18)33-5/h8,12-13,31H,6-7,9-11H2,1-5H3,(H2,23,24,25,26,27)/t12-,13?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 36.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein kinase C beta type
(Homo sapiens (Human)) | BDBM286370
(US11220518, Ex. No. K26 | US11780853, Example K26 ...)Show SMILES COc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C21H31FN8O3/c1-12-9-28(4)13(6-7-31)10-29(12)20(32)30-11-14-16(21(30,2)3)26-27-17(14)24-18-15(22)8-23-19(25-18)33-5/h8,12-13,31H,6-7,9-11H2,1-5H3,(H2,23,24,25,26,27)/t12-,13?/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 54.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q28S4T3T |
More data for this
Ligand-Target Pair | |
Protein kinase C beta type Isoform 2
(Homo sapiens (Human)) | BDBM286370
(US11220518, Ex. No. K26 | US11780853, Example K26 ...)Show SMILES COc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C21H31FN8O3/c1-12-9-28(4)13(6-7-31)10-29(12)20(32)30-11-14-16(21(30,2)3)26-27-17(14)24-18-15(22)8-23-19(25-18)33-5/h8,12-13,31H,6-7,9-11H2,1-5H3,(H2,23,24,25,26,27)/t12-,13?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 54.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human)) | BDBM286370
(US11220518, Ex. No. K26 | US11780853, Example K26 ...)Show SMILES COc1ncc(F)c(Nc2n[nH]c3c2CN(C(=O)N2CC(CCO)N(C)C[C@@H]2C)C3(C)C)n1 |r| Show InChI InChI=1S/C21H31FN8O3/c1-12-9-28(4)13(6-7-31)10-29(12)20(32)30-11-14-16(21(30,2)3)26-27-17(14)24-18-15(22)8-23-19(25-18)33-5/h8,12-13,31H,6-7,9-11H2,1-5H3,(H2,23,24,25,26,27)/t12-,13?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 54.7 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
PFIZER INC.
US Patent
| Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe... |
US Patent US9518060 (2016)
BindingDB Entry DOI: 10.7270/Q2ZK5JPN |
More data for this
Ligand-Target Pair | |