Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM255125
(US9475817, 84)Show SMILES COc1ncc(cn1)C(=O)Nc1cn2nc(ccc2n1)-c1cn(C)nc1-c1ccc(F)cc1 Show InChI InChI=1S/C22H17FN8O2/c1-30-11-16(20(29-30)13-3-5-15(23)6-4-13)17-7-8-19-26-18(12-31(19)28-17)27-21(32)14-9-24-22(33-2)25-10-14/h3-12H,1-2H3,(H,27,32) | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 435 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme, substrates (flu... |
US Patent US9475817 (2016)
BindingDB Entry DOI: 10.7270/Q2JQ0ZXH |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM255125
(US9475817, 84)Show SMILES COc1ncc(cn1)C(=O)Nc1cn2nc(ccc2n1)-c1cn(C)nc1-c1ccc(F)cc1 Show InChI InChI=1S/C22H17FN8O2/c1-30-11-16(20(29-30)13-3-5-15(23)6-4-13)17-7-8-19-26-18(12-31(19)28-17)27-21(32)14-9-24-22(33-2)25-10-14/h3-12H,1-2H3,(H,27,32) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme, substrates (flu... |
US Patent US9475817 (2016)
BindingDB Entry DOI: 10.7270/Q2JQ0ZXH |
More data for this
Ligand-Target Pair | |