Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 529.5 BDBM389708

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM389708 (US9951063, 27) Show SMILES COc1ncc(cn1)N1CCc2c(C1)c(ccc2C(F)(F)F)N1CCN([C@H](C)C1)C(=O)CCn1cccn1 Show InChI InChI=1S/C26H30F3N7O2/c1-18-16-34(12-13-36(18)24(37)7-11-35-9-3-8-32-35)23-5-4-22(26(27,28)29)20-6-10-33(17-21(20)23)19-14-30-25(38-2)31-15-19/h3-5,8-9,14-15,18H,6-7,10-13,16-17H2,1-2H3/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	908	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				Bioorg Med Chem Lett 17: 3473-9 (2007) BindingDB Entry DOI: 10.7270/Q20R9RRK
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