Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 485.0 BDBM235957

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human))	BDBM235957 (US9365539, 60) Show SMILES CS(=O)(=O)N1CCC(C1)N1CCC(CC1)c1cc(nn1-c1ccccc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H29ClN4O2S/c1-33(31,32)29-16-13-23(18-29)28-14-11-20(12-15-28)25-17-24(19-7-9-21(26)10-8-19)27-30(25)22-5-3-2-4-6-22/h2-10,17,20,23H,11-16,18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.1	n/a	n/a	n/a	n/a	5.5	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The assay was run in a 384-well microliter plate at 37° C. with a total volume of 50 uL. Final assay concentrations were 0.13 nM human PrCP (CHO) or ...				US Patent US9365539 (2016) BindingDB Entry DOI: 10.7270/Q22B8WXK
					More data for this Ligand-Target Pair