Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 470.3 BDBM559602

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM559602 (US11370796, Compound 30) Show SMILES CS(=O)(=O)N1CCC(CC1)n1cc(Nc2ncc3c(Cl)cn(C4CC4)c3n2)c(Cl)n1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.02	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description After the compound was dissolved in 100% DMSO at 10 mM, it was serially diluted to the range of 1 μM to 10 μM using biochemical LRRK2 assay...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z7J
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM559602 (US11370796, Compound 30) Show SMILES CS(=O)(=O)N1CCC(CC1)n1cc(Nc2ncc3c(Cl)cn(C4CC4)c3n2)c(Cl)n1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description After the compound was dissolved in 100% DMSO at 10 mM, it was serially diluted to the range of 1 μM to 10 μM using biochemical LRRK2 assay...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z7J
					More data for this Ligand-Target Pair