Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140458
((E)-N-(1-Benzyl-piperidin-4-yl)-N-(1-methanesulfon...)Show SMILES CS(=O)(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C30H33N3O3S/c1-37(35,36)32-21-16-26-13-14-28(22-29(26)32)33(30(34)15-12-24-8-4-2-5-9-24)27-17-19-31(20-18-27)23-25-10-6-3-7-11-25/h2-15,22,27H,16-21,23H2,1H3/b15-12+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]-PYY from human NPYY2 receptor |
Bioorg Med Chem Lett 24: 430-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.061 BindingDB Entry DOI: 10.7270/Q2H133HQ |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140458
((E)-N-(1-Benzyl-piperidin-4-yl)-N-(1-methanesulfon...)Show SMILES CS(=O)(=O)N1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C30H33N3O3S/c1-37(35,36)32-21-16-26-13-14-28(22-29(26)32)33(30(34)15-12-24-8-4-2-5-9-24)27-17-19-31(20-18-27)23-25-10-6-3-7-11-25/h2-15,22,27H,16-21,23H2,1H3/b15-12+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057 BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this Ligand-Target Pair | |