Found 9 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Protein-lysine 6-oxidase
(Homo sapiens (Human)) | BDBM469057
(US10807974, Example 80 | US10995088, Example 80 | ...)Show SMILES CS(=O)(=O)c1ccc(cc1-c1ccccc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C18H17NO4S3/c1-25(20,21)17-9-8-15(11-16(17)13-5-3-2-4-6-13)26(22,23)18-10-7-14(12-19)24-18/h2-11H,12,19H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL
US Patent
| Assay Description The following reagents were prepared:Reagents500 mM CHES, pH 9 (with NaOH), filtered (MW=207.29)20.7 g in 200 ml in dH2O10% Pluronic F-127 (store at ... |
US Patent US10995088 (2021)
BindingDB Entry DOI: 10.7270/Q2125WSK |
More data for this Ligand-Target Pair | |
Protein-lysine 6-oxidase
(Sus scrofa) | BDBM469057
(US10807974, Example 80 | US10995088, Example 80 | ...)Show SMILES CS(=O)(=O)c1ccc(cc1-c1ccccc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C18H17NO4S3/c1-25(20,21)17-9-8-15(11-16(17)13-5-3-2-4-6-13)26(22,23)18-10-7-14(12-19)24-18/h2-11H,12,19H2,1H3 | UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
| Assay Description LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990. |
US Patent US10807974 (2020)
BindingDB Entry DOI: 10.7270/Q2TH8QS8 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Sus scrofa) | BDBM469057
(US10807974, Example 80 | US10995088, Example 80 | ...)Show SMILES CS(=O)(=O)c1ccc(cc1-c1ccccc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C18H17NO4S3/c1-25(20,21)17-9-8-15(11-16(17)13-5-3-2-4-6-13)26(22,23)18-10-7-14(12-19)24-18/h2-11H,12,19H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.Assay Plates:Black, flat bottom 96 well platesProcedure:1. Dilute LOX en... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25M69MF |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM469057
(US10807974, Example 80 | US10995088, Example 80 | ...)Show SMILES CS(=O)(=O)c1ccc(cc1-c1ccccc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C18H17NO4S3/c1-25(20,21)17-9-8-15(11-16(17)13-5-3-2-4-6-13)26(22,23)18-10-7-14(12-19)24-18/h2-11H,12,19H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
| Assay Description MAO-Glo Assay Kit: Promega, Cat No. V1402, MAO-A Enzyme: Promega, Cat No. V1452. |
US Patent US10807974 (2020)
BindingDB Entry DOI: 10.7270/Q2TH8QS8 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM469057
(US10807974, Example 80 | US10995088, Example 80 | ...)Show SMILES CS(=O)(=O)c1ccc(cc1-c1ccccc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C18H17NO4S3/c1-25(20,21)17-9-8-15(11-16(17)13-5-3-2-4-6-13)26(22,23)18-10-7-14(12-19)24-18/h2-11H,12,19H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL
US Patent
| Assay Description The following reagents were prepared:ReagentsMAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. ... |
US Patent US10995088 (2021)
BindingDB Entry DOI: 10.7270/Q2125WSK |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] A
(Homo sapiens (Human)) | BDBM469057
(US10807974, Example 80 | US10995088, Example 80 | ...)Show SMILES CS(=O)(=O)c1ccc(cc1-c1ccccc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C18H17NO4S3/c1-25(20,21)17-9-8-15(11-16(17)13-5-3-2-4-6-13)26(22,23)18-10-7-14(12-19)24-18/h2-11H,12,19H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description MAO-B Enzyme: Sigma, Cat No. M7441Deprenyl: Sigma, Cat No. M003Assay Plates: 96 well white polystyrene, flat bottom plates, no lid: Fisher, Cat No. D... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25M69MF |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM469057
(US10807974, Example 80 | US10995088, Example 80 | ...)Show SMILES CS(=O)(=O)c1ccc(cc1-c1ccccc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C18H17NO4S3/c1-25(20,21)17-9-8-15(11-16(17)13-5-3-2-4-6-13)26(22,23)18-10-7-14(12-19)24-18/h2-11H,12,19H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research: Royal Cancer Hospital
US Patent
| Assay Description MAO-Glo Assay Kit: Promega, Cat No. V1402, MAO-B Enzyme: Sigma, Cat No. M7441. |
US Patent US10807974 (2020)
BindingDB Entry DOI: 10.7270/Q2TH8QS8 |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM469057
(US10807974, Example 80 | US10995088, Example 80 | ...)Show SMILES CS(=O)(=O)c1ccc(cc1-c1ccccc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C18H17NO4S3/c1-25(20,21)17-9-8-15(11-16(17)13-5-3-2-4-6-13)26(22,23)18-10-7-14(12-19)24-18/h2-11H,12,19H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL
US Patent
| Assay Description The following reagents were prepared:ReagentsMAO-Glo Assay Kit: Promega, Cat No. V1402MAO-B Enzyme: Sigma, Cat No. M7441Deprenyl: Sigma, Cat No. M003... |
US Patent US10995088 (2021)
BindingDB Entry DOI: 10.7270/Q2125WSK |
More data for this Ligand-Target Pair | |
Amine oxidase [flavin-containing] B
(Homo sapiens (Human)) | BDBM469057
(US10807974, Example 80 | US10995088, Example 80 | ...)Show SMILES CS(=O)(=O)c1ccc(cc1-c1ccccc1)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C18H17NO4S3/c1-25(20,21)17-9-8-15(11-16(17)13-5-3-2-4-6-13)26(22,23)18-10-7-14(12-19)24-18/h2-11H,12,19H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Promega ROS-Glo H2O2 Assay Kit, 50 ml. Cat No. G8821Inhibitors (Test compounds):10 mM stock diluted to 10, 3, 1, 0.3, 0.1, 0.03, 0.01, 0.003, 0.001, ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q25M69MF |
More data for this Ligand-Target Pair | |