Found 5 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine)) | BDBM50077535
((7-Methanesulfonyl-1,2,3,4-tetrahydro-isoquinolin-...)Show InChI InChI=1S/C11H15NO3S/c1-16(14,15)11-3-2-8-4-10(7-13)12-6-9(8)5-11/h2-3,5,10,12-13H,4,6-7H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of bovine adrenal Phenylethanolamine N-Methyltransferase |
J Med Chem 42: 1982-90 (1999)
Article DOI: 10.1021/jm9807252 BindingDB Entry DOI: 10.7270/Q2959GR6 |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine)) | BDBM50077535
((7-Methanesulfonyl-1,2,3,4-tetrahydro-isoquinolin-...)Show InChI InChI=1S/C11H15NO3S/c1-16(14,15)11-3-2-8-4-10(7-13)12-6-9(8)5-11/h2-3,5,10,12-13H,4,6-7H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Inhibition of PNMT (Phenylethanolamine N-Methyltransferase) in vitro |
J Med Chem 42: 3315-23 (1999)
Article DOI: 10.1021/jm980734a BindingDB Entry DOI: 10.7270/Q2513XD6 |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine)) | BDBM50077535
((7-Methanesulfonyl-1,2,3,4-tetrahydro-isoquinolin-...)Show InChI InChI=1S/C11H15NO3S/c1-16(14,15)11-3-2-8-4-10(7-13)12-6-9(8)5-11/h2-3,5,10,12-13H,4,6-7H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Affinity for bovine Phenylethanolamine N-Methyltransferase |
J Med Chem 42: 3588-601 (1999)
Article DOI: 10.1021/jm990045e BindingDB Entry DOI: 10.7270/Q2NV9HFK |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Bos taurus (bovine)) | BDBM50077535
((7-Methanesulfonyl-1,2,3,4-tetrahydro-isoquinolin-...)Show InChI InChI=1S/C11H15NO3S/c1-16(14,15)11-3-2-8-4-10(7-13)12-6-9(8)5-11/h2-3,5,10,12-13H,4,6-7H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Inhibitory constant against bovine phenylethanolamine N-methyl-transferase |
Bioorg Med Chem Lett 11: 1579-82 (2001)
BindingDB Entry DOI: 10.7270/Q2GF0V17 |
More data for this Ligand-Target Pair | |
Phenylethanolamine N-methyltransferase
(Homo sapiens (Human)) | BDBM50077535
((7-Methanesulfonyl-1,2,3,4-tetrahydro-isoquinolin-...)Show InChI InChI=1S/C11H15NO3S/c1-16(14,15)11-3-2-8-4-10(7-13)12-6-9(8)5-11/h2-3,5,10,12-13H,4,6-7H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas
Curated by ChEMBL
| Assay Description Inhibitory constant against human phenylethanolamine N-methyl-transferase over-expressed in Escherichia coli |
Bioorg Med Chem Lett 11: 1579-82 (2001)
BindingDB Entry DOI: 10.7270/Q2GF0V17 |
More data for this Ligand-Target Pair | |