Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 348.4 BDBM50329988

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA desaturase 1 (Rattus norvegicus (Rat))	BDBM50329988 (2-(biphenyl-4-yl)-7-(methylsulfonyl)imidazo[1,2-a]...) Show SMILES CS(=O)(=O)c1ccn2cc(nc2c1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H16N2O2S/c1-25(23,24)18-11-12-22-14-19(21-20(22)13-18)17-9-7-16(8-10-17)15-5-3-2-4-6-15/h2-14H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of rat SCD1				Bioorg Med Chem Lett 20: 6366-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.094 BindingDB Entry DOI: 10.7270/Q20V8D1P
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM50329988 (2-(biphenyl-4-yl)-7-(methylsulfonyl)imidazo[1,2-a]...) Show SMILES CS(=O)(=O)c1ccn2cc(nc2c1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H16N2O2S/c1-25(23,24)18-11-12-22-14-19(21-20(22)13-18)17-9-7-16(8-10-17)15-5-3-2-4-6-15/h2-14H,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of human SCD1				Bioorg Med Chem Lett 20: 6366-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.094 BindingDB Entry DOI: 10.7270/Q20V8D1P
					More data for this Ligand-Target Pair
Stearoyl-CoA desaturase 5 (Homo sapiens (Human))	BDBM50329988 (2-(biphenyl-4-yl)-7-(methylsulfonyl)imidazo[1,2-a]...) Show SMILES CS(=O)(=O)c1ccn2cc(nc2c1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H16N2O2S/c1-25(23,24)18-11-12-22-14-19(21-20(22)13-18)17-9-7-16(8-10-17)15-5-3-2-4-6-15/h2-14H,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of human SCD5				Bioorg Med Chem Lett 20: 6366-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.094 BindingDB Entry DOI: 10.7270/Q20V8D1P
					More data for this Ligand-Target Pair