Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 536.6 BDBM50285793

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50285793 (4-Oxo-piperidine-1-carboxylic acid {[(R)-1-((1S,2R...) Show SMILES CSC[C@H](NC(=O)CNC(=O)N1CCC(=O)CC1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C26H40N4O6S/c1-17(2)13-22(32)24(34)20(14-18-7-5-4-6-8-18)29-25(35)21(16-37-3)28-23(33)15-27-26(36)30-11-9-19(31)10-12-30/h4-8,17,20-22,24,32,34H,9-16H2,1-3H3,(H,27,36)(H,28,33)(H,29,35)/t20-,21-,22-,24+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition against recombinant human renin (rHR)				Bioorg Med Chem Lett 5: 2623-2626 (1995) Article DOI: 10.1016/0960-894X(95)00456-4 BindingDB Entry DOI: 10.7270/Q2C24WDC
					More data for this Ligand-Target Pair