Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Ketohexokinase
(Homo sapiens (Human)) | BDBM130658
(US8822447, 167 | US9771375, Example 167)Show SMILES CSc1nn(-c2ccccc2)c2cc(NC(=O)C3(F)CCNCC3)ccc12 Show InChI InChI=1S/C20H21FN4OS/c1-27-18-16-8-7-14(23-19(26)20(21)9-11-22-12-10-20)13-17(16)25(24-18)15-5-3-2-4-6-15/h2-8,13,22H,9-12H2,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV
US Patent
| Assay Description An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT... |
US Patent US9771375 (2017)
BindingDB Entry DOI: 10.7270/Q20R9RJW |
More data for this Ligand-Target Pair | |
Ketohexokinase
(Homo sapiens (Human)) | BDBM130658
(US8822447, 167 | US9771375, Example 167)Show SMILES CSc1nn(-c2ccccc2)c2cc(NC(=O)C3(F)CCNCC3)ccc12 Show InChI InChI=1S/C20H21FN4OS/c1-27-18-16-8-7-14(23-19(26)20(21)9-11-22-12-10-20)13-17(16)25(24-18)15-5-3-2-4-6-15/h2-8,13,22H,9-12H2,1H3,(H,23,26) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Pharmaceutica NV
US Patent
| Assay Description An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT... |
US Patent US8822447 (2014)
BindingDB Entry DOI: 10.7270/Q2M0443Q |
More data for this Ligand-Target Pair | |