Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Ketohexokinase
(Homo sapiens (Human)) | BDBM130568
(US8822447, 33 | US9771375, Example 33)Show SMILES CSc1nn(-c2ccccc2)c2cc(ccc12)N1CCN(CC1)C(=O)C1CCCN1 Show InChI InChI=1S/C23H27N5OS/c1-30-22-19-10-9-18(16-21(19)28(25-22)17-6-3-2-4-7-17)26-12-14-27(15-13-26)23(29)20-8-5-11-24-20/h2-4,6-7,9-10,16,20,24H,5,8,11-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 5.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV
US Patent
| Assay Description
An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT... |
US Patent US9771375 (2017)
BindingDB Entry DOI: 10.7270/Q20R9RJW |
More data for this
Ligand-Target Pair | |
Ketohexokinase
(Homo sapiens (Human)) | BDBM130568
(US8822447, 33 | US9771375, Example 33)Show SMILES CSc1nn(-c2ccccc2)c2cc(ccc12)N1CCN(CC1)C(=O)C1CCCN1 Show InChI InChI=1S/C23H27N5OS/c1-30-22-19-10-9-18(16-21(19)28(25-22)17-6-3-2-4-7-17)26-12-14-27(15-13-26)23(29)20-8-5-11-24-20/h2-4,6-7,9-10,16,20,24H,5,8,11-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 5.34E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Pharmaceutica NV
US Patent
| Assay Description
An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT... |
US Patent US8822447 (2014)
BindingDB Entry DOI: 10.7270/Q2M0443Q |
More data for this
Ligand-Target Pair | |