Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 682.1 BDBM363257

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM363257 (2-((5-chloro-2-((3-cyanobenzyl)oxy)-4-((3-(2,3-dih...) Show SMILES Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CNC(Cc3nccs3)C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1 Show InChI InChI=1S/C37H32ClN3O6S/c1-23-27(6-3-7-29(23)26-8-9-32-35(16-26)45-12-11-44-32)22-47-34-18-33(46-21-25-5-2-4-24(14-25)19-39)28(15-30(34)38)20-41-31(37(42)43)17-36-40-10-13-48-36/h2-10,13-16,18,31,41H,11-12,17,20-22H2,1H3,(H,42,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...				US Patent US9850225 (2017) BindingDB Entry DOI: 10.7270/Q2N018TZ
					More data for this Ligand-Target Pair