Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 670.1 BDBM363292

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM363292 (3-((4-chloro-5-((3-(2,3-dihydrobenzo[b][1,4]dioxin...) Show SMILES Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CNCC(O)CN3CCOCC3)cc2Cl)cccc1-c1ccc2OCCOc2c1 Show InChI InChI=1S/C38H40ClN3O6/c1-26-30(6-3-7-33(26)29-8-9-35-38(18-29)46-15-14-45-35)25-48-37-19-36(47-24-28-5-2-4-27(16-28)20-40)31(17-34(37)39)21-41-22-32(43)23-42-10-12-44-13-11-42/h2-9,16-19,32,41,43H,10-15,21-25H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...				US Patent US9850225 (2017) BindingDB Entry DOI: 10.7270/Q2N018TZ
					More data for this Ligand-Target Pair