Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM197561
(US9216968, 161 | US9732066, 161)Show SMILES Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2ccccc2C(F)(F)F)cc2[nH]c(NCC(O)=O)nc12 Show InChI InChI=1S/C25H19ClF3N5O4/c1-12-17(26)7-4-8-18(12)32-23(38)15-9-13(10-19-21(15)34-24(33-19)30-11-20(35)36)31-22(37)14-5-2-3-6-16(14)25(27,28)29/h2-10H,11H2,1H3,(H,31,37)(H,32,38)(H,35,36)(H2,30,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
NIPPON SHINY AKU CO., LTD.
US Patent
| Assay Description
mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu... |
US Patent US9732066 (2017)
BindingDB Entry DOI: 10.7270/Q2K35WSW |
More data for this
Ligand-Target Pair | |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM197561
(US9216968, 161 | US9732066, 161)Show SMILES Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2ccccc2C(F)(F)F)cc2[nH]c(NCC(O)=O)nc12 Show InChI InChI=1S/C25H19ClF3N5O4/c1-12-17(26)7-4-8-18(12)32-23(38)15-9-13(10-19-21(15)34-24(33-19)30-11-20(35)36)31-22(37)14-5-2-3-6-16(14)25(27,28)29/h2-10H,11H2,1H3,(H,31,37)(H,32,38)(H,35,36)(H2,30,33,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
NIPPON SHINYAKU CO., LTD.
US Patent
| Assay Description
mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu... |
US Patent US9216968 (2015)
BindingDB Entry DOI: 10.7270/Q2KS6QCQ |
More data for this
Ligand-Target Pair | |