Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50395270
(CHEMBL2163609)Show SMILES Cc1c(N[C@H]2CCCNC2)nc2ccnn2c1Nc1ccc(cc1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C24H31N7O/c1-16-22(27-20-7-4-13-25-15-20)30-21-12-14-26-31(21)23(16)28-19-10-8-17(9-11-19)24(32)29-18-5-2-3-6-18/h8-12,14,18,20,25,28H,2-7,13,15H2,1H3,(H,27,30)(H,29,32)/t20-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Teijin Pharma Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of MAPKAP-K2 using KKLNRTLSVA as substrate and [33P]-gamma-ATP after 30 mins by liquid scintillation counter |
J Med Chem 55: 6700-15 (2012)
Article DOI: 10.1021/jm300411k
BindingDB Entry DOI: 10.7270/Q20K29PX |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50395270
(CHEMBL2163609)Show SMILES Cc1c(N[C@H]2CCCNC2)nc2ccnn2c1Nc1ccc(cc1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C24H31N7O/c1-16-22(27-20-7-4-13-25-15-20)30-21-12-14-26-31(21)23(16)28-19-10-8-17(9-11-19)24(32)29-18-5-2-3-6-18/h8-12,14,18,20,25,28H,2-7,13,15H2,1H3,(H,27,30)(H,29,32)/t20-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Teijin Pharma Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of CDK2 after 60 mins using [33P]-gamma-ATP by liquid scintillation counter |
J Med Chem 55: 6700-15 (2012)
Article DOI: 10.1021/jm300411k
BindingDB Entry DOI: 10.7270/Q20K29PX |
More data for this
Ligand-Target Pair | |