Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 432.4 BDBM50576819

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50576819 (CHEMBL4868114) Show SMILES Cc1c(O)c(ccc1OCCCCOc1ccc(C(O)=O)c(F)c1)C(=O)CC(C)(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulator activity at rat mGlu2 receptor transfected in GIRK channel overexpressing cells assessed as potentiation of glutamate-i...				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128342 BindingDB Entry DOI: 10.7270/Q22F7S71
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50576819 (CHEMBL4868114) Show SMILES Cc1c(O)c(ccc1OCCCCOc1ccc(C(O)=O)c(F)c1)C(=O)CC(C)(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulator activity at rat mGlu3 receptor transfected in GIRK channel overexpressing cells assessed as potentiation of glutamate-i...				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128342 BindingDB Entry DOI: 10.7270/Q22F7S71
					More data for this Ligand-Target Pair